Home Population Genomics Resources Population Genomics Projects Krutovsky's Lab Links Contact

Population Genetics Course:   GENE-612


 When:   TR  02:20PM - 03:35PM  
Where:   Biochemistry & Biophysics Bldg (BICH) , room 106A




Download:
  • Syllabus
  • Additional Errata for Hedrick, PW (2005) Genetics of Populations, 3rd ed. Jones & Bartlett Publishers, Sudbury, MA compiled by K.V. Krutovsky
  • Additional Errata for Hedrick, PW (2010) Genetics of Populations, 4th ed. Jones & Bartlett Publishers, Sudbury, MA compiled by K.V. Krutovsky
  • Software
  • Lecture notes, homework assignments and solutions:


week 1 - week 2 - week 3 - week 4 - week 5 - week 6
week 7 - week 8 - week 9 - week 10 - week 11
week 12 - week 13 - week 14 - week 15 - week 16


Week Topic Date Lecture or Activity Chapter reading
1 General Background and the Diversity of Genetic Variation Aug 30


Sep 1
1. Introduction to Population Genetics (history, paradigm, approaches, tools, etc.)

2. Patterns and Types of Genetic Variation & Markers; Review of some Math and Probability Theory

Problem set/homework #1 due to Sep 8
---


Ch. 1
2 Measures of Genetic Variation Sep 6


Sep 8
3. Hardy-Weinberg Principle and Measures of Genetic Variability

4. Factors that affect genetic variation

Problem set/homework #2 due to Sep 15
Ch. 2

PS Solutions #1
3 Selection: An Introduction Sep 13

Sep 15
5. Basic Selection Model

6. Estimation of Selection

Problem set/homework #3a due to Sep 22
Ch. 3a

PS Solutions #2
4 Selection: Advanced Topics Sep 20

Sep 22
7. Forms of selection

8. Ecological genetics

Problem set/homework #3b due to Sep 29
Ch. 3b

PS Solutions #3a
5 Genetic Drift and Effective Population Size Sep 27


Sep 29
9. Genetic Drift and Effective Population Size

10. Genetic Drift and Selection

Problem set/homework #4 due to Oct 6
Ch. 4

PS Solutions #3b
6 Mutation Oct 4

Oct 6
11. Mutation

12. Mutation (cont.)

Problem set/homework #5 due to Oct 20
Ch. 5

PS Solutions #4
7 Mid-term exam preparation Oct 11



Oct 13
13. Genetic drift and selection simulation software. Problem set/homework discussion and exercise.

14. Mid-term exam

8 Neutral Theory and Coalescence Oct 18


Oct 20
15. Neutral Theory and Predictions about Molecular Variation, Neutrality Tests

16. Coalescence and Gene Genealogies

Problem set/homework #6 due to Oct 27
Ch. 6

PS Solutions #5
9 Gene Flow and Population Structure Oct 25

Oct 27
17. Gene flow and Population Structure

18. Population Structure Models

Problem set/homework #7 due to Nov 3
Ch. 7

PS Solutions #6
10 Inbreeding Nov 1

Nov 3
19. Estimation of Inbreeding

20. Inbreeding and Selection

Problem set/homework #8 due to Nov 10
Ch. 8

PS Solutions #7
11 Linkage Disequilibrium and Recombination Nov 8


Nov 10
21. Linkage Disequilibrium & Recombination

22. Multilocus Selection

Problem set/homework #9 due to Nov 17
Ch. 9

PS Solutions #8
12 Molecular Phylogenetics, Evolution & Population Genomics Nov 15

Nov 17
23. Molecular Evolution & Phylogenetics

24. Population Genomics

Project Highlights / Software demonstration / PS Discussion
Ch. 6, III;
Ch. 7, IIId;
Ch. 9, VI

PS Solutions #9
13 Projects Nov 22



Nov 24
25. Final lecture / Preparations for the final exam
  • Presentation schedule

    26. Thanksgiving (no class)


  • 14 Projects Nov 29






    Dec 1
    27. Student presentations / Discussion
  • Josephine Antwi
  • Robert Britt
  • Colleen Fisher
  • Mary Gorton
  • Angela Hawkins

    28. Student presentations / Discussion
  • Trevis Huggins
  • Roel Lerma
  • Victor Mason
  • Megan Norton
  • Elizabeth Richey

  • 15 Projects

    Dec 6







    Dec 8
    29. Student presentations / Discussion
  • Anas Khanshour
  • Rodriguez Ostilio
  • Joana Rocha
  • Cory Thurman
  • Kylee Veazey
  • Mallory Williams

    30. Reading day (no class)
  •  
    16 Final Exam Dec 12 (Mon) 31. Final Exam (1:00 to 5:00 PM) (solutions)  


    Site Under Construction